Action of Fufang Danpu Decoction on experimental gastric ulcer
- VernacularTitle:复方丹蒲汤抗实验性胃溃疡的作用
- Author:
Ping YANG
;
Shiping MA
- Publication Type:Journal Article
- Keywords:
Fufang Danpu Decoction;
gastric ulcer model;
secretion of gastric juice;
gastric emptying;
analgesia
- From:
Chinese Traditional Patent Medicine
1992;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To study the action of Fufang Danpu Decoction(FFDPD) on experimental gastric ulcer in mice. METHODS: The anti-gastric ulcer action of FFDPD was observed on the gastric ulcer induced by water immersion stress,absolute ethyl alcohol,reserpine and pyloric ligation.The effect on gastric secretion in rats was studied by pyloric ligation.The effect on gastrointestinal motility was observed by gastric emptying in mice. The analgesic effect was tested by the hot-plate test. RESULTS: FFDPD markedly inhibited gastric ulcer induced by water immersion stress,absolute ethyl alcohol,reserpine and pyloric ligation.FFDPD significantly inhibited the secretion of gastric acid and pipsin.FFDPD markedly delayed gastric emptying and enhanced hot pain threshold in mice. CONCLUSION: FFDPD may have anti-gastric ulcer effect,in relation to its inhibition of the secretion of gastric juice,of activity of gastric smooth muscle and analgetic effect.
