The effects of extremely low frequency rectangular pulsed electromagnetic fields on rat osteoblast
- VernacularTitle:极低频电磁场对成骨细胞增殖与分化的影响
- Author:
Xiaojun ZHANG
;
Jianbao ZHANG
;
Jun WEN
;
Xuemin QU
- Publication Type:Journal Article
- Keywords:
Electromagnetic fields;
Osteoblast;
Proliferation;
Differentiation
- From:
Chinese Journal of Physical Medicine and Rehabilitation
2003;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate of the biological effects of the extremely low frequency electromagnetic fields (ELFEMF),and to explore the effect of rectangular ELFEMF performance parameters on rat fetal skull osteoblast. Methods Different amplitude, frequency and duty cycle of rectangular ELFEMF were used on rat fetal skull osteoblast and the proliferation and differentiation of osteoblast were examined. Results There existed action windows of amplitude and frequency with regard to the biological effect of rectangular ELFEMF. The 15 Hz, 5 mT and 15% duty cycle could significantly promote the proliferation and decrease differentiation of the cells. Conclusion The proliferation and differentiation of osteoblast could be affected by rectangular ELFEMF characterized by its amplitude, frequency and duty cycle. This study indicated that rectangular ELFEMF of 15 Hz, 5 mT and 15% duty cycle was suitable for the proliferation and differentiation of osteoblast in vitro.
