Ophiopogon samponin Ⅵ?Release rate of ophiopogon saponin enteric microsphere
- VernacularTitle:麦冬皂苷研究Ⅶ?麦冬皂苷肠溶微球的释放度研究
- Author:
Lan SHEN
;
Yi FENG
;
Desheng XU
;
Xiao LIN
- Publication Type:Journal Article
- Keywords:
ophiopogon saponin enteric microspere;
release rate
- From:
Chinese Traditional Patent Medicine
1992;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To explore the influencing factors in the release rate and give the application to the preparation. METHODS: Preparing ophiopogon saponin enteric microsphere by spray drying process,the accumulative release rate of acid and buffer solution were detected by colorimetric analysis. RESULTS: With the increase of Eudragit Ⅱ concentraction,the accumulative release rate tended to decrease.But ratio of drug and Eudragit Ⅱ,increased with the decrease in delay time on the break point. CONCLUSION: The concentration of Eudragit and the ratio of drug and material are the rey factors in the accumulative release rate in acid and buffer solution.
