Infulence of regulating liver-qi and tonifying kidney recipes on hypothalamus-pituitary-ovary axis in rats under psychologic stress
- VernacularTitle:舒肝方对心理应激肝郁大鼠神经生殖内分泌的作用
- Author:
Baomin HUANG
;
Xihao WANG
;
Guanting ZHANG
- Publication Type:Journal Article
- Keywords:
relieving liver-qi;
psychologic stress;
syndrome of liver-qi stagnation;
neuro reproductive;
endocrine;
monoamine neurotransmitter;
sexual hormone;
rat
- From:
Chinese Traditional Patent Medicine
1992;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To investigate the effect of relieving liver-qi recipes(Radix Bupleuri,Radix Paeoniae Alba,Fructus Aurantii,etc.) on the neuro reproductive endocrine in female rats under psychologic stress. METHODS: The psychologic stress induced syndrome of liver-qi stagnation in female rats was established by tail pinch.The hypothalamus pituitary and serum levels of NE,DA,5 HT,5-HIAA,DOPAC,HVA and the serum FSH,LH,E2,T,P,PRL in rats of any groups were measured. RESULTS: The levels of NE in hypothalamus pituitary and FSH,LH,E2,P in serum of model rats were lower and the contents of DA,5-HT,5-HIAA in hypothalamus pituitary and in serum and NE,T in serum were significantly higher than those of the normal control.The serum P and LH in the complex group were elevated.The descending NE in hypothalamus pituitary and FSH,E2 in serum increased and the ascended DA,5-HT,5-HIAA in hypothalamus pituitary and NE,5-HT,T in serum significantly descresed in the shugan group and the complex group.The enhance of NE in hypothalamus pituitary and FSH,P in serum and the reduction of 5-HT in hypothalamus pituitary and 5-HT,NE,T in serum were also obversed in the bushen group. CONCLUSION: Regulating liver-qi and tonifying the kidney recipes could improve the function of neuro reproductive endocrine system which could be attenuated or disturbed by psychologic stress.
