Studies on the Water-extraction Process in "Leifengguan” Granules
- VernacularTitle:“类风关”颗粒水提取工艺研究
- Author:
Lin CHEN
;
Zhenli LIU
;
Wenlai WANG
- Publication Type:Journal Article
- Keywords:
“Leifengguan” granules;
TLC-scanning;
Astragaloside IV;
Orthogonal design
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2006;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To select the best condition of preparation process for the water-extraction and alcohol-precipitation method of Radix astragali in “Leifengguan” granules. Methods The effective compound astragaloside IV of Radix astragali was determined with the methods of TLC-scanning. The preparation process was screened with orthogonal design [L9(34)] and single factor analysis. Results The best condition of preparation process for water-extraction of Radix astragali was A3B2C2 that the drug materials were decocted for 3 times with 8 times amount of water, each time for 1 hour. After the solution was concentrated to proportion as 1 g/mL (drug materials/solution), alcohol was added to the solution to 60% alcohol. Conclusions The optimized preparation process was found to be stable with a good reproducibility.
