EXPRESSION OF COLLAGEN I BY IMMUNOHISTOCHEMISTRY AND IN SITU HYBRIDIZATION IN RAT HEART
- VernacularTitle:大鼠心脏Ⅰ型胶原的免疫组织化学和原位杂交表达
- Author:
Zhikun GUO
- Publication Type:Journal Article
- Keywords:
Collagen I;
In situ hybridization;
Heart;
Rat
- From:
Acta Anatomica Sinica
1953;0(01):-
- CountryChina
- Language:Chinese
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Abstract:
Objective To probe distribution and excreting cells of type I collagen in rat heart. Methods Expression of cardiac collagen I was detected using immunohistochemistry and in situ hybridization. Results Type I collagen was distributed in myocytes,and it encased each cardiac cell.The densities of collagen network in difference cardiac part were of disparity.Type I collagen was all expressed in fibrcyte and smooth muscle cells and endothelial cells in blood vessels of cardiac tissue.Conclusion The type I collagen is a main component of cardiac fibrous network,and its excreting cells are multifocal.
