Meta-analysis for relationship between different instillation methods and recurrence in superficial bladder carcinoma after surgical operation
- VernacularTitle:浅表膀胱癌不同灌注方法与复发的荟萃分析
- Author:
Jiangang PAN
;
Ruifa HAN
- Publication Type:Journal Article
- Keywords:
Meta-analysis;
Bladder neoplasms;
Instillation,regional;
Recurrence
- From:
Chinese Journal of General Practitioners
2002;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of different instillation methods on recurrence of superficial bladder carcinoma after surgical operation by meta-analysis.Methods Literatures in the relationship between different instillation methods and recurrence of superficial bladder carcinoma issued from January 1989 to February 2005 were retrieved and the effects were quantitatively estimated with fixed-effect model and random-effect model by meta-analysis.Results Forty-three copies of related literatures were included in the analysis.Combined OR of the instillation methods excluding BCG,only BCG instillation and combined instillation of BCG and other drugs for the recurrence of bladder carcinoma after surgical operation was 0.55(95%CI:0.40~0.74),0.32(95%CI:0.06~1.64) and 0.43(95%CI:0.33~0.57),respectively.Funnel plot showed symmetrically distributed studies,indicating little publication bias and reliable conclusions.Conclusions Only BCG instillation and combined instillation of BCG and other drugs could effectively lower recurrence of superficial bladder carcinoma after surgical operation.
