Determination of Rutin in Circanetten New Tablets by HPLC
- VernacularTitle:HPLC法测定强力痔根断片中芦丁的含量
- Author:
Hong LI
- Publication Type:Journal Article
- Keywords:
HPLC;
Circanetten New tablets;
Rutin;
Content determination
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
1993;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To determine the content of rutin in Circanetten New tablets by HPLC. Methods The determination is performed at C18(150 mm? 4.6 mm, 5 ? m) column with temperature being 30 ℃ ; the mobile phase is consisted of methanol- water- glacial acetic acid(40 ∶ 60 ∶ 1.8) and UV detection wavelength is at 354 nm. Results The linear range was 6.008 to 48.064 ? g/mL( r=0.999 9) for Circanetten New tablets and the average recovery of rutin was 100.3% (RSD=0.5 % , n=5) .Conclusion The method is simple and effective, and can be used to control the quality of Circanetten New tablets.