Preparation Technology of Extraction and ? - cyclodextrin Inclusion of Volatile Oil in Shaofu Zhuyu Tablets
- VernacularTitle:少腹逐瘀片挥发油提取与?-环糊精包合工艺研究
- Author:
Jiancheng TANG
;
Shudan ZHANG
- Publication Type:Journal Article
- Keywords:
Shaofu Zhuyu Tablets;
Volatility oil;
? - cyclodextrin;
Orthogonal test
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
1993;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the optimum conditions of extraction and ? - cyclodextrin inclusion for the volatile oil from Radix Angelicae Sinensis, Rhizoma Chuanxiong and Cortex Cinnamomi in Shaofu Zhuyu Tablets. Methods The extraction conditions were evaluated by the ultimate oil extract ratio with single- factor analysis, and the inclusion technology were optimized by the inclusion output ratio and oil- bearing ratio in the inclusion with orthogonal test. Results The optimum conditions for extraction were as follows: smashing the medicinal material into coarse powder (through 10- mesh screen), adding 8 times of the water (mwater ∶ mpander=8 ∶ 1), extracting oil for 4 hours. The best conditions for inclusion were as: the ratio of Oil and ? - cyclodextrin being 1 mL ∶ 8g, and stirring for 2 hours at 50 ℃ . Conclusion The extraction and inclusion conditions in this study are optimal with high oil extract rate, reasonable inclusion process, and minimum cost.
