The effects of electroacupuncture combined with transcranial magnetic stimulation on VEGF164 mRNA and CD31 expression in rats with cerebral ischemia
- VernacularTitle:电针结合经颅磁刺激对脑缺血大鼠VEGF164 mRNA和CD31表达的影响
- Author:
Xiaolin HUANG
;
Xiaohua HAN
- Publication Type:Journal Article
- Keywords:
Electroacupuncture;
Magnetic stimulation;
VEGF164 mRNA;
CD31;
Cerebral ischemical
- From:
Chinese Journal of Physical Medicine and Rehabilitation
2004;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effect of electroacupuncture(EA) combined with transcranial magnetic stimulation(TMS) on the angiogenesis in rats with cerebral ischemia. Methods Fifty-five male Wistar rats were randomly divided into five groups: a normal group, a model group, an EA group, a TMS group and an EA plus TMS group. After the establishment of acute middle cerebral artery occlusion (MCAO), the rats in various groups were accordingly treated with EA, TMS or EA plus TMS, respectively. Then the expression of VEGF164 mRNA and CD31 was observed. Results The expression of VEGF164 mRNA and CD31 around the infarction locus of the three treatment groups increased, especially in the EA plus TMS group. Conclusion EA plus TMS can increase the expression of VEGF164 mRNA and CD31 around the infarction locus and promote the non-molecular angiogenesis in rats with cerebral ischemia.