The effects of hyperbaric oxygen therapy on promotion of intellectual rehabilitation in infants with severe hypoxic-ischemic encephalopathy
- VernacularTitle:高压氧促进重度缺氧缺血性脑病新生儿智能康复的疗效观察
- Author:
Hong JIANG
;
Ruopeng SUN
- Publication Type:Journal Article
- Keywords:
Hyperbaric oxygen;
Hypoxic-ischemic encephalopathy;
Newborn;
Intelligence
- From:
Chinese Journal of Physical Medicine and Rehabilitation
2004;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the long-time effects of hyperbaric oxygen(HBO) therapy on the promotion of intellectual rehabilitation in infants with severe hypoxic-ischemic encephalopathy(HIE). Methods Forty-seven infants with severe HIE were randomly divided into a HBO group(n=24) and a control group(n=23). All the infants were treated with routine therapy for three months,in addition to HBO treatment in the HBO group once a day for four courses of 10 d with the interval of 10~15 d. Neonatal Behavioral Neurological Assessment (NBNA)assay was employed at 7 and 28 d after born,and Bayley Scale of Infant Development (BSID)assay was got at two years in two groups, as well as Wechsler Preschool and Primary Scale of Intelligence(WPPSI)assay at five years, in order to evaluated the short-time and long-time effects of HBO on intellectual rehabilitation in infants with HIE. Results Compared with that in the control group, the score of NBNA in the HBO group was significantly higher at 28 d(P
