Determination of four components in Shengmai Injection by HPLC
- VernacularTitle:HPLC测定生脉注射液中4种成分的含量
- Author:
Jing XIA
;
Gangli WANG
- Publication Type:Journal Article
- Keywords:
Shengmai Injection;
HPLC;
ginsenoside Rg_1;
ginsenoside Re;
ginsenoside Rb_1;
schisandrin
- From:
Chinese Traditional Patent Medicine
1992;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To establish a method of simultaneous determining 4 components in Shengmai Injection (Radix et Rhizoma Ginseng Rubra,Radix Ophiopogonis,Fructus Schisandrae Chinensis). METHODS: Four components:ginsenoside Rg_1、ginsenoside Re、ginsenoside Rb_1 and schisandrin in Shengmai Injection were determined simultaneously by HPLC, using a waters symmetryshield TMRP_(18) column(4.6 mm?250 mm; 5.0 ?m),acetonitrile-water as a mobile phase. The detection wavelength was at 203nm. RESULTS: The relationship between the concentrations and the peak areas of ginsenoside Rg_1、ginsenoside Re、ginsenoside Rb_1 and schisandrin was linear respectively.The RSD of precision,repeatability and recovery were all less than 1%. CONCLUSION: The method is simultaneous determination for four components in Shengmai Injection,and can be applied to the quality control of Shengmai Injection.
