Effect of the group of effective components of Chinese medical prescription-Xiaoxuming Decoction on aging rats
- VernacularTitle:复方“小续命汤”有效成分组对试验性衰老大鼠的作用
- Author:
Yuehua WANG
;
Guanhua DU
- Publication Type:Journal Article
- Keywords:
Chinese medical prescription;
group of effective components(GEC);
D-galactose;
rotenone;
aging
- From:
Chinese Traditional Patent Medicine
1992;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To establish the model of aging rats and observe the effect of the group of effective components of Xiaoxuming Decoction(XXM)on aging rats. METHODS: D-galactose and rotenone were used to establish aging animal model.The ability of learning and memory were measured by using Morris water maze test.Then, the content of GSH and MDA,the activity of SOD,the activity of AchE and ChAT in rats'brain were measured. (RESULTS): D-galactose could induce aging like indicators in rats:decrease the content of GSH and the activity of SOD,and increase the content of MDA,but have no effect on AchE and ChAT.It showed that GEC could improve the ability of learning and memory and ameliorate biochemistry function in rats with aging induced by D-galactose. CONCLUSION: These results suggest that GEC of XXM could improve the responses of aging rats and these effects may be related to its ability of antioxidation.
