Lipo-alkaloids in Sini Decoction stemmed from ester-exchange reactions
- VernacularTitle:四逆汤中脂类生物碱来源于酯交换反应的研究
- Author:
Yong WANG
;
Fengrui SONG
;
Zhiqiang LIU
;
Shuying LIU
- Publication Type:Journal Article
- Keywords:
Sini Decoction;
prepared aconite root(Radix Aconiti Lateralis Preparata);
ESI-MS~n;
ester-exchange reaction
- From:
Chinese Traditional and Herbal Drugs
1994;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the solubility of lipo-alkaloids from prepared aconite root(Radix Aconiti Lateralis Preparata) and identify the sources of lipo-alkaloids in Sini Decoction.Methods The electrospray ionization mass spectrometry was employed to analyze the alkaloids in crude aconite roots,Sini Decoction,the gruffs of concocted aconite roots and the decoction of prepared aconite root and pinellia tuber(Rhizoma Pinellae).Results Lipo-alkaloids were observed in Sini Decoction,however,no lipo-(alkaloids) were found in the decoction of aconite roots with pinellia tuber.Lipo-alkaloids were the dominant components in the gruffs of concocted aconite roots.Conclusion Lipo-alkaloids are barely soluble in boiling water.The alkaloids existed in the Sini Decoction stem from the ester-exchange reactions of diester-diterpenoid alkaloids and fatty acid in the boiling water.
