Effects of local mild hypothermia treatment on plasma neuropeptide Y (NPY), neurotensin (NT), calcitonin gene-related peptide (CGRP) and endotheline (ET) in patients with cerebral hemorrhage
- VernacularTitle:局部亚低温对脑出血后血管活性物质的影响
- Author:
Xiuzhou ZHANG
;
Xueping LIU
;
Wenhua LI
;
Rui CHEN
- Publication Type:Journal Article
- Keywords:
Local mild hypothermia;
Cerebral hemorrhage;
Vaso-active substance
- From:
Chinese Journal of Emergency Medicine
2006;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of local mild hypothermia treatment on plasma vaso-active substance such as neuropeptide Y(NPY),neurotensin(NT),calcitonin gene-related peptide(CGRP) and endotheline(ET) in patients with acute cerebral hemorrhage. Methods 70 patients were randomly divided into two groups: local mild hypothermia group (35 patients) and routine treatment group (35 patients).Nineteen healthy persons served as control group. Routine treatment was used in the both groups, and the local mild hypothermia therapy was only used in local mild hypothermia group. NPY, NT, CGRP and ET in plasma at the 1 day, 7 days and 14 days after onset were assessed.Results The concentrations of NT, CGRP and ET in the plasma of the two group were markedly higher than control group before treatment (P
