The change of nuclear factor ?B activity in peripheral blood monocytes in patients with acute coronary syndrome
- VernacularTitle:核因子?B活性在急性冠状动脉综合征中的变化
- Author:
Ping SHU
;
Di LIU
;
Huiyun ZHOU
- Publication Type:Journal Article
- Keywords:
Nuclear factor ?B;
Monocyte in peripheral blood;
Inflammation reaction;
Acute coronary syndrome
- From:
Chinese Journal of Emergency Medicine
2006;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the role of nuclear factor ?B activation in the onset of acute coronary syndrome(ACS).Methods 76 patients with acute myocardial infraction(AMI),41 patients with unstable angina pectoris(UAP),43 patients with stable angina pectoris(SAP)and 20 normal controls were enrolled.NF-?B activation in monocytes in peripheral blood monocyte was determined by ELISA with the NF-?B p65 Kit the at 3 and 5 days after admission.Results The activity of NF-?B in monocytes of peripheral blood in AMI patients and UAP patients was significantly higher than that in SAP patients and normal controls(P
