Effect of Yiqi Fuzhi Granule in Activating Blood Circulation and Removing Blood Stasis in Rat Models of Multiple Infarctional Dementia
- VernacularTitle:益气复智颗粒对多发梗死性痴呆模型大鼠的活血化瘀作用
- Author:
Jianying ZHOU
;
Dongping YAN
;
Tao LIU
;
Xuefeng LIU
- Publication Type:Journal Article
- Keywords:
Yiqi Fuzhi Granule;
Multiple infarctional dementia;
Rats;
Blood rheology;
Activate blood circulation and remove blood stasis
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
2000;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of Yiqi Fuzhi Granule on activating blood circulation and removing blood stasis in rat models of multiple infarctional dementia.Methods Internal carotid artery injection method was used to establish rat models of multiple infarctional dementia.The changes of blood rheology,blood platelet aggregation,thromboplastin time,plasmozyme time and kaolin partial thromboplastin time before and after operation were observed.Results Yiqi Fuzhi Granule could markedly improve blood rheology in rat models of multiple infarctional dementia and reduce blood viscosity and blood platelet aggregati on rate,the effect being obvious before operation.Conclusion Yiqi Fuzhi Granule has a good action of activating blood circulation and removing blood stasis.