Quality control of autoantibody detection in China
- VernacularTitle:国内自身抗体检测的现状及质控分析
- Author:
Jing HE
;
Rulin JIA
;
Zhanguo LI
- Publication Type:Journal Article
- Keywords:
Antibodies;
Quality control;
Analysis
- From:
Chinese Journal of Rheumatology
2003;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the quality of autoantibodies detection in China. Method Standardized samples were sent to 73 laboratories that are able to detect autoantibodies. The autoantibodies detected included antinuclear antibody (ANA), anti-dsDNA antibody, anti-extractable nuclear antigen (ENA) antibody, anti-mitochondrial antibody (AMA) and anti-smooth muscle antibody (ASMA). The analysis of testing results was double-blinded. Result The consistent rates of ANA, anti-dsDNA antibody, anti-ENA antibody, anti-mitochondrial antibody and anti-smooth muscle antibody were 86.2%, 75.4%, 62.7%, 100% and 61.1% respectively. Conclusion The overall accuracy has been elevated, but still needs to be improved.