Study on compatibility of the nHA/PA composite implant
- VernacularTitle:纳米羟基磷灰石／聚酰胺复合材料人工肱骨头的体内生物相容性研究
- Author:
Jian ZHANG
- Publication Type:Journal Article
- Keywords:
Arthoplasty;
Hydroxyapatite;
Polyamide;
Biocompatability
- From:
Journal of Chongqing Medical University
2003;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To evaluate the compatibility of the nHA/PA composite implant. Methods: The component was implanted into the proximal humeral metaphysis of rabbits. The prosthetic humeral head replacement was performed in 20 rabbits. The rabbits were killed at the 3rd, 6th, 12th, 24th week after operation. Specimens were observed by histology and immunohistochemitry. Results; Immuno-histochemistry results showed that there were some CD4+ , CD8+ lymphocytes infiltrated into the interface at the 3rd week, without other inflammatory cells being observed. While at 6th, 12th, 24th week, neither lymphocytes nor inflammatory cells were seen. Conclusion; The nHA/PA prostheses show good biocompatibility.
