Comparative study on use therapeutic efficacy of single of Morphine and drug combined medication
- VernacularTitle:单用吗啡与联合用药治疗转移性骨肿瘤疼痛疗效比较
- Author:
Qiong LUO
- Publication Type:Journal Article
- Keywords:
Drug combination, Bone metastatic carcinoma, Pain, Cost
- From:
Journal of Chongqing Medical University
2003;0(06):-
- CountryChina
- Language:Chinese
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Abstract:
Objective; To study the efficacy, side effect and economic value of morphine controlled - release tablets plus diclofenac sodium and antidepressive drugs in the treatment of pain caused by metastatic bone carcinoma. Methods: 83 patients with pain of meta-static bone carcinoma were randomly divided into two groups. Group I was treated only with morphine controlled - release tablets, Group II with morphine controlled - release tablets, diclofenac sodium and amitriptyline. The dosage of morphine controlled - release tablets, the adverse reaction and the medical cost were observed. Results: The dosage of morphine controlled - release tablets and the medical cost in Group II were obviously lower than those in Group I. The side effects were not significantly different between the two groups. Conclusions: Morphine controlled - release tablets plus diclofenac sodium and antidepressive drugs can treat the pain of metastatic bone carcinoma effectively, relieve the economic burden of the patient while not to increase the side effects.
