Qualitative analysis of the marker peaks of Shuanghuanglian Powder-Injection fingerprints and its synergy
- VernacularTitle:双黄连粉针剂指纹图谱中特征色谱峰的组成药味归属及定性
- Author:
Jie ZHANG
- Publication Type:Journal Article
- Keywords:
Shuanghuanglian Powder-Injection;
fingerprints;
synergy;
qualitative analysis of chromatographic peaks
- From:
Chinese Traditional Patent Medicine
1992;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To qualitatively analyse the marker peaks of Shanghuanglian Powder-Injection(Flos Lonicerae Japonicae,Radix Scutellariae,Fructus Forsythiae,etc.) fingerprints and determine their synergy. METHODS: The HPLC-PDA/ELSD fingerprints of Shuanghuanglian Powder Injection were compared with those of component herbs.The relative retention time of each peak,the Ultraviolet spectra providing by PDA and some pure standard substances were used in the analyses. RESULTS: Thirteen marker common peaks of HPLC-PDA(254 nm) fingerprint and HPLC-ELSD fingerprint were confirmed to the three component herbs respectively.Four marker peaks were identified as chlorogenic acid,caffeic acid,baicalin and phillyroside. CONCLUSION: Some marker peaks and their synergy origins can be identified by chromatographic fingerprint technology in the Chinese traditional patent medicine.
