THE EFFECT OF CALCITONIN GENE RELATED PEPTIDE AND NERVE GROWTH FACTOR ON THE EXPRESSION OF c-jun mRNA AND PROTEIN IN STRIATE CORTEX OF RATS WITH TRANSIENT GLOBAL CEREBRAL ISCHEMIA/REPERFUSION
- VernacularTitle:降钙素基因相关肽和神经生长因子对短暂性全脑缺血后再灌注大鼠纹皮质c-jun mRNA及蛋白表达的影响
- Author:
Dacheng JIN
;
Tiemin WANG
;
Xiubin FANG
- Publication Type:Journal Article
- Keywords:
Cerebral ischemia;
c-jun;
Calcitonin gene related peptide;
Nerve growth factor;
Striate cortex;
In situ hybridization;
Immunohistochemistry;
Rat
- From:
Acta Anatomica Sinica
2002;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effects of calcitonin gene related peptide(CGRP) and nerve growth factor(NGF) on the expression of(c-junmRNA) and protein in striate cortex of rats with transient global cerebral ischmia/reperfusion. Methods In situ hybridization,immunohistochemistry and microscope image analysis were used. Results The expression of c-jun mRNA in ischemia/reperfusion(I/R) group was increased as compared with sham group(P
