HPLC determination for four constituents in Danqi Tablet
- VernacularTitle:丹七片中4种成分的HPLC定量测定
- Author:
Guiru HAN
;
Shaojie ZHANG
;
Zhenlin YAO
;
Lei YANG
- Publication Type:Journal Article
- Keywords:
Danqi Tablet;
sodium salvianic A;
protocatechualdehyde;
notoginsenoside R_1;
ginsenoside Rg_1;
HPLC
- From:
Chinese Traditional Patent Medicine
1992;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To establish a method for the quality control of Danqi Tablet(Radix et Rhizoma Salviae Miltiorrhizae,Radix et Rhizoma Notoginseng,etc). METHODS: The content of salvianic A and protocatechualdehyde,notoginsenoside R_1 and ginsenoside Rg_1 in Danqi Tablet were determined simultaneously respectively by HPLC. RESULTS: The methodological study showed that a good linear correlation existed in the range of 0.164-3.28 ?g(r=0.999 99) of sodium salvianic A,0.013-0.52 ?g(r=0.999 999) of protocatechualdehyde,0.2-6 ?g(r=0.999 997) of notoginsenoside R_1 and 0.824-24.72 ?g(r=0.999 96) of ginsenoside Rg_1,respectively.The average recovery of sodium salvianic A was 98.34%(n=9),RSD was 2.03%,100.65% for protocatechualdehyde(n=9),RSD was 2.96%,98.97% for notoginsenoside R_1(n=9),RSD was 2.81%;98.93% for ginsenoside Rg_1(n=9),RSD was 0.57%. CONCLUSION: The determination methods are simple,accurate and reproducible.The method can be used for quality control of Danqi Tablet.
