Effects of Tongqiao Huoxue Decoction on contents of CGRP、 ET、 IL-1?、TNF-? in the brains of rats of cerebral ischemia
- VernacularTitle:通窍活血汤对脑缺血大鼠脑组织中CGRP、ET、IL-1?、TNF-?的影响
- Author:
Ning WANG
;
Qingyun LIU
;
Daiyin PENG
;
Min DAI
;
Quan ZHU
- Publication Type:Journal Article
- Keywords:
Tongqiao Huoxue Decoction;
cerebral ischemia;
IL-I?;
TNF-?
- From:
Chinese Traditional Patent Medicine
1992;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To investigate the protective effects and mechanisms of Tongqiao Huoxue Decoction on the rats of cerebral ischemia. METHODS: Cerebral ischemia madel was established on the basis of cerebral thrombus and at the same time ligaturing bilateral carotid arteries.These models were used to observe the protective effects of Tongqiao Huoxue Decoction on contents of CGRP、ET、IL-1?,TNF? in rats′ cerebral ischemica. RESULTS: The results showed that Tongqiao Huoxue Decoction decreased the contents of IL-1?、TNF-?、 ET,and increased the contents of CGRP. CONCLUSION: Tongqiao Huoxue Decoction had effects on anti-cerebral ischemia.The protective effects of Tongqiao Huoxue Decoction are related to decreasing the contents of IL-1?,TNF-?,ET,and increasing the contents of CGRP.
