Determination of Ephedrine Hydrochloride in Xiaochuanning Capsules by HPLC
- VernacularTitle:HPLC法测定哮喘宁胶囊中盐酸麻黄碱的含量
- Author:
Xiangyang LI
;
Wanqian TU
- Publication Type:Journal Article
- Keywords:
Xiaochuanning capsules;
Ephedrine Hydrochloride;
HPLC;
Content determination
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
2000;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To develop a HPLC method for the determination of ephedrine hydrochloride in Xiaochuanning capsules.Methods A Hypersil ODS column was used.The mobile phase was acetonitrile-water solution of 0.05 mol / L NaH2PO4(pH2.7,22 ∶ 78).The flow rate was 1.0 mL / min and column temperature was 40 ℃.Detcted wavelength was 205 nm.Results A good linearity was in the range of 0.1005 ~ 0.5025 ?g(r = 0.9993).The average recovery was 103.1 %,RSD=1.81 %.Conclusion The method is simple,accurate,and can be used for the quality control of Xiaochuanning capsules.
