Comparison between Ropivacaine and Ropivacaine combined with Clonidine for Spinal Anaesthesia
- VernacularTitle:罗哌卡因与罗哌卡因复合可乐定行蛛网膜下腔阻滞的临床研究
- Author:
Xinwei LIU
- Publication Type:Journal Article
- Keywords:
Ropivacaine;
Clonidine;
Spinal anesthesia
- From:
Journal of Chongqing Medical University
2003;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:This study was to evaluate the effect of Ropivacaine for the spinal anaesthesia and the quality of analgesia and anaesthesia when clonidine was added.Methods:Spinal anaesthesia was administered to 32 ASA Ⅰ~Ⅱ degree adult patients who were randomly divided into two groups: Ropivacaine group [R=16] and Ropivacaine + Clonidine group .Data collected included;T10 spread time,maximum upper sensory level reached,and onset time and duration of zero power motor blockades,T12 regression time,pain onset time,and sedation score were also recorded.Results:The RC group onset of the T10 spread time was shorter,the maximum upper sensory level reached was higher,the onset time of zero power motor block was faster;The RC group anaesthetic regression time,the duration of zero power motor block,the time of pain onset was longer,and sedation scores was higher.Conclusion:Ropivacaine and ropivacaine combined with clonidine are sufficient to produce good sensory and motor blockade for lower abdomen and lower limb surgery under spinal anaesthesia.Addition of clonidine to Ropivacaine increase the anaesthetic potency by shortening onset time of sensation and motor block,increasing maximum upper sensory block level,prolonging regression time,and prolonging duration of the analgesic period as well as providing some sedation.