Effects of electroacupuncture on the expression of Nestin in neural stem cell after focal cerebral ischemia in rats
- VernacularTitle:电针对局灶性脑缺血大鼠神经干细胞巢蛋白表达的影响
- Author:
Zhe LIU
;
Xinsheng LAI
- Publication Type:Journal Article
- Keywords:
Focal cerebral ischemia;
Neural stem cell;
Nestin;
Electroacupuncture
- From:
Chinese Journal of Physical Medicine and Rehabilitation
2003;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the influence of electroacupuncture on the expression of Nestin in neural stem cells after focal cerebral ischemia in rats and to explore the mechanism of electroacupuncture in treating ischemic brain injury. Methods The model of middle cerebral artery occlusion was made by using opening cranium hot coagulation in 72 rats, who were divided randomly into a model group and an electroacupuncture group. Electroacupuncture was applied on "Dazhui" and "Baihui" points in rats in electroacupuncture group, and immunohistochemistry method was used to observe the number of Nestin expression positive cells on the 3th, 7th, 14th and 21st days after ischemia. Results There were Nestin positive cells in the cortex, hippocampal dentate gyrus (DG) and striatum at different time points after cerebral ischemia, and the number of Nestin positive cells in various brain regions were increased significantly on the 7th day (P
