Molding process of Tongluo Mini-Pill by rotary pelletizer
- VernacularTitle:旋转式制丸技术在通络微丸成型工艺中的应用研究
- Author:
Liuqing DI
;
Hong SHEN
;
Ke YAN
;
Shengjin LIU
;
Yeqing ZHANG
;
Houru XIE
- Publication Type:Journal Article
- Keywords:
Tongluo Mini-Pill;
excipient;
PEG_ 2000;
gum arabic;
rotary pelletizer
- From:
Chinese Traditional Patent Medicine
1992;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To choose the proper excipient for molding process of Tongluo Mini-Pill (Radix Astragali,Radix Augelicae sinensis,Flos longicerae Japonicae,etc) and couplet its production. METHODS: A variety of excipients properties such as fluidity,solubility and dissolution were compared to select and determine the processing parameters of rotary perlletizer. RESULTS: Recommendation was made applying processing parameters that 10% PEG_ 2000 ,10% PEG_ 2000 or 10% gum arabic used for excipient,pelletizer had a rotational velosity of 100 rpm.pressure of 0.04 Mpa and feeding rate of 1200 g?min -1 . CONCLUSION:Selection of excipients is a key to make Tonglu Mini-Pill.
