Effects of mild hypothermia on endothelial cell of cerebral vessels in patients with moderate or severe cerebral infarction
- VernacularTitle:亚低温对中重度脑梗死患者血管内皮细胞功能的影响
- Author:
Xinghan HUANG
;
Xiaoli ZOU
- Publication Type:Journal Article
- Keywords:
Mild hypothermia;
Cerebral infarction;
Endothelial cell
- From:
Chinese Journal of Physical Medicine and Rehabilitation
2003;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effects of mild hypothermia on endothelial cell of cerebral vessels in patients with moderate or severe cerebral infarction. Methods Sixty patients with moderate or severe cerebral infar-ction were divided into 2 groups: a mild hypothermia group (30 cases) and a non-mild hypothermia group (30 cases). Endothelin (ET), endothelial nitric oxide synthases(eNOS) and von Willebrand factor(vWF) were tested with RIA or ELISA. All the patients were treated with routine medication, in addition, those in mild hypothermia group were also treated with mild hypothermia. Results The ET and vWF levels of serum and cerebrospinal fluid (CSF) in patients of mild hypothermia group were significantly lower than those of non-mild pothermia group (P
