Prenatal diagnosis of prelingual deafness by determination of SLC26A4 gene mutation
- VernacularTitle:学语前性耳聋疾病相关基因的产前诊断
- Author:
Hao HU
;
Lingqian WU
;
Desheng LIANG
;
Yong FENG
;
Fang CAI
;
Kun XIA
;
Qian PAN
;
Zhigao LONG
;
Heping DAI
;
Jiahui XIA
- Publication Type:Journal Article
- Keywords: Prenatal diagnosis; Deafness; Membrane transport proteins; Mutations
- From: Chinese Journal of Obstetrics and Gynecology 2000;0(09):-
- CountryChina
- Language:Chinese
- Abstract: G mutation of SLC26A4, the parents and the second child were carriers of the same mutation, while the fetus had a wild-type form. Conclusion It is feasible to identify deafness related genes by screening for GJB2 and SLC26A4 mutation, thus providing correct prenatal diagnosis and avoiding deaf delivery of baby.