An experimental study of inhibitory effect of SFAS on human hepatic carcinoma cell line SMMC-7721 in vitro
- VernacularTitle:红藤脂酸钠对人肝癌细胞系SMMC-7721体外抑瘤作用的实验研究
- Author:
Tao LIU
;
Zhimin WANG
;
Jianxue WEI
- Publication Type:Journal Article
- Keywords:
SFAS;
Human hepatic carcinoma cell line;
SMMC-7721;
Apoptosis
- From:
Journal of Interventional Radiology
1994;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the inhibitory effect of SFAS on the growth of human hepatic carcinoma cell line SMMC-7721 in vitro and discuss its mechanism. Methods The inhibitory fraction of SMMC-7721 cells was measured by MTT assay, and both of the Annexin V and TUNEL assays were used to determine the apoptotic proportion. Results The value of the control group was (0.385?0.03), and that of the SFAS groups (250 ?g/ml, 500 ?g/ml, 1 mg/ml and 2 mg/ml) were (0.31?0.019), (0.199?0.022), (0.150?0.033) and (0.048?0.026) respectively, with significant difference statistically ( P
