Clinical application of quantitative computed tomography in osteogenesis imperfecta-suspected cat.
10.4142/jvs.2017.18.3.415
- Author:
Sungjun WON
1
;
Woo jo CHUNG
;
Junghee YOON
Author Information
1. Irion Animal Hospital, Seoul 06015, Korea.
- Publication Type:Case Report
- Keywords:
cats;
metabolic bone diseases;
osteogenesis imperfecta;
quantitative computed tomography
- MeSH:
Animals;
Bone Density;
Bone Diseases, Metabolic;
Cats*;
Congenital, Hereditary, and Neonatal Diseases and Abnormalities;
Diagnosis;
Fractures, Multiple;
Humans;
Male;
Osteogenesis Imperfecta;
Osteogenesis*;
Radiography
- From:Journal of Veterinary Science
2017;18(3):415-417
- CountryRepublic of Korea
- Language:English
-
Abstract:
One-year-old male Persian cat presented with multiple fractures and no known traumatic history. Marked decrease of bone radiopacity and thin cortices of all long bones were identified on radiography. Tentative diagnosis was osteogenesis imperfecta, a congenital disorder characterized by fragile bone. To determine bone mineral density (BMD), quantitative computed tomography (QCT) was performed. The QCT results revealed a mean trabecular BMD of vertebral bodies of 149.9 ± 86.5 mg/cm³. After bisphosphonate therapy, BMD of the same site increased significantly (218.5 ± 117.1 mg/cm³, p < 0.05). QCT was a useful diagnostic tool to diagnose osteopenia and quantify response to medical treatment.
