Clinical Study of Ganxian Granules Ⅰ for the Treatment of Liver Fibrosis Induced by Chronic Virus Hepatitis
- VernacularTitle:肝纤Ⅰ号冲剂对慢性病毒性肝炎肝纤维化的临床疗效的影响
- Author:
Junling ZUO
- Publication Type:Journal Article
- Keywords:
HEPATITIS, CHRONIC/TCD therapy;
LIVER CIRRHOSIS/TCD therapy;
GANXIAN GRANULES Ⅰ/therapeutic use;
ACTIVATING BLOOD AND REMOVING STASIS
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
2000;0(04):-
- CountryChina
- Language:Chinese
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Abstract:
[Objective] To observe the therapeutic effect of Ganxian Granules Ⅰ (mainly composed of Radix Stephani-ae Tetrandrae, Semen Persicae and Radix Notoginseng) for the treatment of liver fibrosis induced by chronic virus hepatitis. [Methods] Two hundred cases of liver fibrosis induced by chronic virus hepatitis were randomized into group A (n = 120) and group B ( n = 80). Group A received Ganxian Granules Ⅰ 10g per day, tid, and group B received Dahuang Zhechong Pills 9g per day, tid for half a year. The therapeutic effect in the two groups was evaluated after treatment. The changes of hepatic function and serum levels of hyaluronidase (HA) , laminin (LN) and type Ⅲ precolla-gen ( PC Ⅲ) were compared before and after treatment. Meanwhile, type B ultrasonographic results and hepatic pathologic features were observed. [Results] The total therapeutic effective rate was 87.5% in group A, higher than 70.0% in group B ( P 0.05). Group A had a better effect in improving the hepatic function than group B (P
