Effect of Weichangshu Capsule on Experimental Gastric Ulcer
- VernacularTitle:胃肠舒胶囊抗实验性胃溃疡作用的研究
- Author:
Ji LIN
;
Xianglu RONG
;
Ping HUANG
;
Youliang XIE
;
Ziren SU
;
Xuejun ZHAO
- Publication Type:Journal Article
- Keywords:
Weichangshu capsule;
Gastric ulcer;
Pharmacodynamics
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
1993;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of Weichangshu Capsule (WCSC) in inhibiting experimental gastric ulcer and the damage of gastric mucosa in SD rats. Methods The experimental gastric ulcer rat models were established by ligation of pylorus, water immersing method and subcutaneous injection of indometacin, and rat models with acute damage of gastric mucosa were induced by hydrochloric acid- ethanol (HAE).Then the effect of WCSC in inhibiting experimental gastric ulcer and the damage of gastric mucosa in SD rats were observed. Results WCSC had obviously inhibitory effects on stress gastric ulcer, indometacin- induced gastric ulcer and HAE- induced acute damage of gastric mucosa. WCSC also inhibited the secretion of gastric juice and increased pepsase activity. Conclusion WCSC has counteraction on experimental gastric ulcer.
