Determination of the Protocatechualdehyde in Maodongqing Sustained- release Tablet by RP- HPLC
- VernacularTitle:RP-HPLC法测定毛冬青缓释片中原儿茶醛的含量
- Author:
Yuanxin LI
;
Xujiang YUAN
;
Shenshang ZHU
- Publication Type:Journal Article
- Keywords:
Maodongqing Sustained- release Tablet;
Protocatechualdehyde;
RP- HPLC;
Content determination
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
1993;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Object To establish a new method to determine protocatechualdehyde in Maodongqing Sustained- release Tablet. Methods The RP- HPLC method was applied with CH3OH and 1 % acetic acid as mobile phase, flowrate at 1.0 mL/min, and detection wavelength at 312 nm. Results In the range from 11.7 ng to 140.4 ng, protocatechualdehyde was in a good line with peak area, r=0.99995, the average recovery ratio was 96.41 % , RSD=1.04 % (n=5). Conclusions It was the first time to establish the RP- HPLC method to determine and control the protocatechualdehyde in Maodongqing Sustained- release Tablet with accuracy and a good reproducibility.
