Effect of cytochrome P450 2C19 genetic polymorphisms on efficacy of rabeprazole or omeprazole-based triple therapy for eradication of Helicobacter pylori
- VernacularTitle:根除幽门螺杆菌疗效与细胞色素氧化酶P450 2C19基因多态性的关系
- Author:
Yingjie JIANG
;
Yuyuan LI
;
Yuqiang NIE
- Publication Type:Journal Article
- Keywords:
Helicobacter pylori;
Proton pump inhibitor;
Gene polymorphism
- From:
Chinese Journal of Digestion
2001;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
0.05). However in OAC group, there were significant differences between EM and IM(P0.05). Conclusions RAC and OAC triple therapy could eradicate H. pylori effectively. The efficacy of rabeprazole-based triple therapy was less affected by the CYP2C19 genotype. The eradication rates of H. pylori in PM and IM were higher than that in EM.
