Effect of Gardenia jasminoides Ellis on serum IL-1? and TNF-? of rheumatoid arthritis rats
- VernacularTitle:栀子对类风湿性关节炎大鼠血清IL-1?和TNF-?的影响
- Author:
Jiang ZHU
;
Wenli XIE
;
Yuzhang JIN
;
Wenjun SUN
;
Xin GAO
- Publication Type:Journal Article
- Keywords:
Gardenia jasminoides Ellis;
rheumatoid arthritis;
IL-1?;
TNF-?
- From:
Chinese Traditional Patent Medicine
1992;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM To study the effect of Gardenia jasminoides Ellis on serum IL-1? and TNF-? level of rheumatoid arthritis rats, as well as its mechanism. METHODS An experimental type Ⅱ collagen-induced arthritic rats was established. The inhibitory effects on paw edema were observed, and serum IL-1? and TNF-? levels were determined in experimental rats. RESULTS Compared with models, Gardenia jasminoides Ellis inhibited paw edema on rats significantly, and the levels of serum IL-1? and TNF-? showed markedly decrease by Gardenia jasminoides Ellis at high dose to medium dose( P
