Alkaloids isolated from Buyang Huanwu Decoction and their structure identification
- VernacularTitle:补阳还五汤中生物碱类化合物的分离与结构鉴定
- Author:
Jun WU
;
Pengfei TU
;
Yuying ZHAO
- Publication Type:Journal Article
- Keywords:
Buyand Huanwu Decoction(BHD);
alkaloids;
N-(3′-maleimidyl)-5-hydroxymethyl-2-pyrrole formaldehyde;
4-carbamoyl-2-pyrrole carboxylic acid;
N-(1′-Ddeoxyxylitolyl)-6,7-dimethyl-1,4-dihydro-2,3-quinoxalinedione
- From:
Chinese Traditional and Herbal Drugs
1994;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the antithrombotic compounds and bioactive fraction from Buyang(Huanwu) Decoction(BHD).Methods Four alkaloids have been isolated from BHD by repeated chromatographies.Their structures were elucidated by means of spectral and single-crystal Xray diffraction analysis.Results They are N-(3′-maleimidyl)-5-hydroxymethyl-2-pyrrole formaldehyde(Ⅰ),4-carbamoyl-2-pyrrole carboxylic acid(Ⅱ),N-(1′-D-deoxyxylitolyl)-6,7-dimethyl-1,4-dihydro-2,3-quinoxalinedione(Ⅲ),and 2,3,4,9-tetrahydro-1H-pyrido indole-3-carboxylic acid(Ⅳ).Conclusion All these compounds are isolated from BHD for the first time and compounds Ⅰ-Ⅲ are new alkaloids.
