Study on the angiogenic ability of tumor vascular endothelial cells
- VernacularTitle:肿瘤基质血管内皮细胞血管形成能力研究
- Author:
Hongmei ZHU
- Publication Type:Journal Article
- Keywords:
Tumor;
Endothelial cell;
Vasculature;
Angiogenesis
- From:
Journal of Chongqing Medical University
1986;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the angiogenic ability of vascular endothelial cells in solid tumors.Methods:Immunocytochemistry,reverse transcription polymerase chain reaction (PT-PCR),and two-well co-culture system were used to detect the expressions of matrix metalloproteinase 9(MMP-9),transforming growth factor-?1(TGF-?1),tenascin(TN)and bcl-2,telomerase activity,and their ability of both migration and tube formation of ECV304-SKOV3 cells respectively,which ,as the cell model,had been established in our laboratory before.Then their abilities of protein synthesis and adhesion were analysed.Results:The ability to synthesize proteins and telomerase activity was enhanced(P
