The expression of survivin and its relationship with the expression of bcl-2 and bax protein in glioma
- VernacularTitle:survivin在脑胶质瘤中的表达及其与bcl-2、bax相关性的研究
- Author:
Quanhong SHI
- Publication Type:Journal Article
- Keywords:
Glioma;
Survivin;
Apoptosis;
Bcl-2;
Bax
- From:
Journal of Chongqing Medical University
1986;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the expression of apoptosis related gene survivin and its relationship with the expression of bcl-2,bax protein in glioma.Methods:Expression of survivin,bcl-2 and bax protein was detected by immunohistochemical method(SP) in 40 cases of glioma,and compared with those in 10 cases of normal brain tissue.The correlation between them was analyzed.Results:The expression rate(42.5%) of survivin protein in glioma was much higher than that(0%) in normal brain tissue(P