Clinical analysis of anticentromere antibodies positive in 26 cases
- VernacularTitle:26例抗着丝点抗体阳性分析
- Author:
Pu CHEN
- Publication Type:Journal Article
- Keywords:
Anticertromere antibodies;
Systemic sclerosis;
Raynaud phenomenon
- From:
Journal of Chongqing Medical University
1986;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To comprehend the clinical significance of anticentromere antibodies(ACA)positive in patients.Methods:A total of 26 patients with positive ACA were studied retrospectively.Results:There were 10 patients with systemic sclerosis(38.4%),4 patients with systemic lupus erythematosus(15.4%),3 patients with Sjogren's syndrome and rheumatoid arthritis(11.5%)respectively,2 patients with mixed connective tissue disease and Raynaud phenomenon(7.7%)respectively,1 patient with CREST syndrome and 1 patient with liver disease of unknown causes (3.8%).ACA and other autoantibodies were present in serum at the same time.Conclusion:ACA is found in many diseases.ACA is not specific for CREST syndrome.The major clinical characteristics of the patients correlated with ACA are Raynaud phenomenon(53.8%)and scleroderma(34.6%).
