- Author:
Jang W YOON
1
;
Carolyn J HOVDE
Author Information
- Publication Type:Review
- Keywords: enterohemorrhagic; Escherichia coli; O157:H7
- MeSH: Animals; Cattle; Cattle Diseases/blood/epidemiology; Developing Countries; *Enterohemorrhagic Escherichia coli; Escherichia coli Infections/blood/*epidemiology/veterinary; *Escherichia coli O157/genetics/pathogenicity; Feces/microbiology; Hemolytic-Uremic Syndrome/blood/epidemiology/veterinary; Operon; Shiga Toxins/analysis; Shigella dysenteriae; Virulence
- From:Journal of Veterinary Science 2008;9(3):219-231
- CountryRepublic of Korea
- Language:English
- Abstract: Enterohemorrhagic Escherichia coli serotype O157:H7 is a pathotype of diarrheagenic E. coli that produces one or more Shiga toxins, forms a characteristic histopathology described as attaching and effacing lesions, and possesses the large virulence plasmid pO157. The bacterium is recognized worldwide, especially in developed countries, as an emerging food-borne bacterial pathogen, which causes disease in humans and in some animals. Healthy cattle are the principal and natural reservoir of E. coli O157:H7, and most disease outbreaks are, therefore, due to consumption of fecally contaminated bovine foods or dairy products. In this review, we provide a general overview of E. coli O157:H7 infection, especially focusing on the bacterial characteristics rather than on the host responses during infection.