Remarks on the effectiveness of hypertonic saline-epinephrine solution and polidocanol solution in the treatment of bleeding peptic ulcer
- Author:
Thai Ba Co
- Publication Type:Journal Article
- Keywords:
gastrointestinal hemorrhage
- MeSH:
Peptic Ulcer;
Therapeutics;
Epinephrine;
Polyethylene Glycols
- From:Journal of Practical Medicine
2005;510(4):23-25
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Prospective study on 107 bleeding peptic ulcer patients treated at Hospital No 103 from July 2001 to December 2002. Participants were divided into 2 groups. Group 1 received hemostatic therapy with polidocanol solution (PLS). Group 2 were treated by hypertonic saline-epinephrine (HSE) solution. Results: The general rate of successful hemostasis was 96.3%, in PLS group was 92.3% and in HSE group was 100%. There were not differences in the rates of initial hemostasis between 2 groups (p>0.05). Hemostatic effect was achieved after the first injection in 76.9% (40 patients) of PLS group and in 85.5% (47 patients) of HSE group. Some patients needed 2nd injections (PLS group: 15.4%, HSE group: 3.7%). Both solutions were effective in the treatment of bleeding peptic ulcer. HSE solution is safe, simple, low cost, and appropriate in Vietnam.
