Effect of Auricularia auriculajudae polysaccharide on cell immunity of tumor-bearing mice
- VernacularTitle:黑木耳多糖对荷瘤小鼠细胞免疫功能的影响研究
- Author:
Xiujuan ZHANG
- Publication Type:Journal Article
- Keywords:
Auricularia auriculajudae polysaccharide(AAP);
anti-tumor effect;
the cellar immune function;
tumor-bearing mice
- From:
Chinese Traditional Patent Medicine
1992;0(06):-
- CountryChina
- Language:Chinese
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Abstract:
AIM: To study the influence of Auricularia auriculajudae polysaccharide (APP) on celular immunity of mice bearing tumor. METHODS: Influence of AAP on lymphocyte proliferaton and IL-2 production of H_(22) mice and was observed by cell cultivation. And the influence of AAP on free Ca~(2+) concentration in lymphocytes of H_(22) mice through laser sacanning confocal microscope (LSCM). RESULTS: AAP can lengthen the average survival time of H_(22) tumor-bearing mice. The research of immune function indicated that AAP can improve the tumor-bearing mice's celular immunity the increase in lymphocytes, and the product of IL-2 and Ca~(2+) concentration inside lymphocytes. CONCLUSION:AAP has a function of anti-tumor. The mechanism has a relation to raising the celular immunity.
