A comparative study of the clinical characteristics and EEG in children with epileptic spasm of different age groups

VernacularTitle:不同年龄组儿童癫痫性痉挛的临床与脑电图特点的比较研究
Author: Li CHEN ; Yan CHEN ; Jianxiang LIAO ; Yana XU ; Weiyan CHEN ; Yan HU ; Jialun WEN ; Bing LI ; Tieshuan HUANG
Publication Type:Journal Article
Keywords: spasm; epilepsy; age distribution; brain mapping
From: Chongqing Medicine 2013;(35):4268-4270,4273
CountryChina
Language:Chinese
Abstract: Objective To compare the clinical and electroencephalogram(EEG)characteristics and therapeutic response prognosis of different age groups of children with epileptic spasm .Methods From January 2002 to October 2011 the clinical data ,EEG fea-tures of epileptic spasms children under 15 years old with unknown disease cause(cryptogenic) were retrospectively reviewed .74 of them were followed up for 12 to 92 months .All of them were divided into two groups on the basis of onset age :3 -12 months of onset as group infantile-onset spasms(group IOS ,n=60);and 12 months to 7 years old of onset as group late-onset epileptic spasms (group LOS ,n=14) .Clinical process ,seizure semiology and EEG features were compared between two groups .Results Semiologic features of two groups were similar ,but they showed differences in interictal EEG features including the background ,the location of discharges ;The response to drugs between the two groups are also different .Conclusion There are differences between group IOS and group LOS when comparing EEG features and response to drugs .