Detection and its significance of human Stanniocalcin-1 mRNA in the peripheral blood from patients with colorectal cancer
- VernacularTitle:大肠癌患者外周血人类斯钙素基因的检测及其意义
- Author:
Peilin HUANG
;
Pingping WU
;
Baoan CHEN
- Publication Type:Journal Article
- Keywords:
Human stanniocalcin-1;
Colorectal cancer;
Peripheral blood;
Reverse transcriptase polymerase chain reaction
- From:
Chinese Journal of Digestion
1996;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the relationship between the expression of human Stanniocalcin-1(hSTC-1) mRNA in the peripheral blood from patients with colorectal cancer and its malignant behavior. Methods RT-PCR was used to detect hSTC-1 mRNA in the peripheral blood from 57 patients with colorectal cancer. The peripheral blood from 14 patients with gastrointestinal inflammatory diseases, 15 healthy volunteers and 5 pregnant women were served as controls. Results The positive rate of hSTC-1 mRNA in 57 patients with colorectal cancer was 49.12% (28/57), and the mRNA expression of hSTC-1 was significantly related with the clinical stage of colon cancer (P
