Effect of Qidan Tongmai Tablet on Ca~(2+) and ultrastructure of myocardial cell in rats
- VernacularTitle:芪丹通脉片对大鼠心肌细胞Ca~(2+)及超微结构的影响
- Author:
Jing MA
- Publication Type:Journal Article
- Keywords:
Qidan Tongmai Tablet (QDTMT);
acute myocardial ischemia;
Ca~(2+);
ultrastructure
- From:
Chinese Traditional and Herbal Drugs
1994;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the protective effect of Qidan Tongmai Tablet (QDTMT) on the (injury) induced by acute myocardial ischemia. Methods Acute myocardial ischemia was induced by sc isoproterenol (Iso, 5 mg/kg) into SD rats pretreated with ig QDTMT (2 g/kg) for two weeks. Activities of Ca~(2+)-(ATPase) in myocardial mitochondria and content of Ca~(2+) in myocardium and myocardial mitochondria were determined by colorimetric method. The changes of myocardial ultrastructure were investigated by means of transmission electron microscope. Results Compared with the controls, activities of Ca~(2+)-(ATPase) in mitochondrion were strengthened in QDTMT group and the content of Ca~(2+) was decreased ((P
