Expression of TNF-? from celiac macrophage after immunization of H37Ra in mice
- VernacularTitle:结核菌H37Ra免疫小鼠后巨噬细胞TNF-?表达的初步探讨
- Author:
Kun TAO
- Publication Type:Journal Article
- Keywords:
H37Ra;
Tumor necrosis factor-?;
Mycobacterium tuberculosis;
Macrophage
- From:
Journal of Chongqing Medical University
1986;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the activity of tumor necrosis factor-?(TNF-?)from celiac macrophage after immunization of H37Ra in mice.Methods:The activity of TNF-? from celiac macrophage was measured by biological method at 30 th day and 60 th day after subcutaneous immunization and celiac immunization of H37Ra in mice.Results:After immunization of H37Ra in mice,the activity of TNF-? by celiac immunized route and subcutaneous immunized route was 22.06U/ml and 22.63U/ml respectively at 30 th day;and it was 36.76U/ml and 33.78U/ml respectively at 60 th day.The activity of TNF-? immunized with H37Ra at 30 th day and 60 th day was much higher than that of non-immunization group( P 0.05),however,the activity of TNF-? in H37Ra immunization group was much higher than that in BCG immunization group at 60 th day( P
