An investigation of reliability on breast-feeding to infants of hepatitis B virus markers positive mothers by active and passive immunization
- VernacularTitle:乙型肝炎病毒携带产妇预防干预措施与母乳喂养的安全性研究
- Author:
Jianhua ZHANG
- Publication Type:Journal Article
- Keywords:
Hepatitis B virus;
Breast-feeding;
Polymerase chain reaction (PCR);
Deoxyribonucleic acid (DNA)
- From:
Journal of Chongqing Medical University
1986;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To provide evidence instruction for breast-feeding,the investigation of positive rates with serum hepatitis B virus markers(HBVM) in infants of breast-feeding to HBVM positive mothers.Methods:The serum HBVM of pregnant women and their infants were determined by ELISA and HBV-DNA in positive serum and colostrum were determined by fluorescence quantitative PCR.The relation between HBVM in the infant serum and the feeding way was analysed.Results:In 67 parturients with serum HBVM antigen positive,the positive rates of HBV-DNA were 84%,26% and 27%,0% in serum and colostrum with HBeAg positive and HBeAg negative mothers;and there was a positive relationship between the serum and colostrum.The positive rates of HBeAg of mothers were 41% and 13% in the artificial feeding group and breast feeding group,there was significant difference between them( P 0.05).Conclusion:The breast-feeding were safe to HBVM positive mothers by active and passive immunization with pregnant women and their infants.
