Life Support Systems in Terms of Energy.
- Author:
Choon Hak LIM
1
;
Hye Won LEE
;
Kyung SUN
;
Ho Sung SON
;
Jung Joo LEE
;
Hae Ja LIM
;
Suk Min YOON
;
Seong Ho CHANG
Author Information
1. Department of Anesthesiology and Pain Medicine, Korea University College of Medicine, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
centrifugal pump;
energy equivalent pressure;
pulsatility
- MeSH:
Aorta;
Arterial Pressure;
Blood Pressure;
Carotid Arteries;
Carotid Artery, Internal;
Catheters;
Extracorporeal Circulation;
Heart Arrest;
Heart Atria;
Hemodynamics;
Humans;
Life Support Systems*;
Models, Animal;
Perfusion;
Research Personnel;
Swine
- From:Anesthesia and Pain Medicine
2006;1(2):92-95
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: The pro's and con's of pulsatile versus nonpulsatile perfusion during acute and chronic mechanical circulatory support is a longstanding controversial issue, some investigators have suggested that the simplest explanation for this controversy is a failure to quantitate adequately the pulsatile components of flow in studies. The aim of this study was to examine the pulsatility generated by centrifugal pump (CP) and a pulsatile extracorporeal life support (twin pulse life support, T-PLS) in terms of energy equivalent pressure (EEP) and surplus hemodynamic energy (SHE). METHODS: In each of the 5 cardiac arrested pigs, the outflow cannula of the CP or T-PLS was inserted into the ascending aorta, and the inflow cannula of the CP or T-PLS was placed in the right atrium. Extracorporeal circulation was maintained for 30 minutes using a pump flow of 75 ml/kg/min by CP or T-PLS, respectively. Pressure and flow were measured in the right internal carotid artery. RESULTS: No statistical difference was observed between CP and T-PLS in terms of mean carotid artery pressure. However, pulse pressure, the percent change from mean arterial pressure to EEP, and SHE in T-PLS were higher than CP (pulse pressure: 36.1 +/- 3.6 mmHg vs 9.1 +/- 1.3 mmHg, P < 0.05, the percent change from mean arterial pressure to EEP: 19.8 +/- 6.2% vs 0.2 +/- 0.3%, P < 0.05). CONCLUSIONS: In a cardiac arrested animal model, CP revealed nonpulsatility and pulsatility generated by T-PLS was effective in terms of EEP and SHE.
